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Parkinson's Non Motor Symptoms

Non Motor Symptoms

The non motor symptoms can include anxiety, depression, apathy, constipation amongst others.

It is important to note that everybody experiences different combinations of symptoms and people do not experience all of the symptoms. 

Cardiovascular

Low Blood Pressure

Low blood pressure when changing positions, such as standing from sitting, can be part of Parkinson's or a side effect of Parkinson's medications.

https://www.parkinsons.org.uk/information-and-support/low-blood-pressure

Shortness of
Breath

Some people with Parkinson's may experience shortness of breath when their symptoms are going off and before their next dose of levodopa medication. Some people can experience respiratory dyskinesia which is an occurrence of irregular and rapid breathing, typically occurring when levodopa medications reach their peak effect. This is typically accompanied by dyskinesia (writhing movements) of other body parts.

https://www.parkinson.org/understanding-parkinsons/non-movement-symptoms/breathing

Emotions & Feelings

Feeling anxious, tense or nervous

Anxiety is not simply a reaction to a Parkinson's diagnosis, but is instead a part of the disease itself, caused by changes in the brain chemistry of the brain and can affect many people with Parkinson's. 40% of people with Parkinson's can suffer from anxiety. This can also be a symptom during the menstrual cycle, peri-menopause, menopause and post menopause for some women with Parkinson's

https://www.parkinson.org/understanding-parkinsons/non-movement-symptoms/anxiety

Shortness of
Breath

Some people with Parkinson's may experience shortness of breath when their symptoms are going off and before their next dose of levodopa medication. Some people can experience respiratory dyskinesia which is an occurrence of irregular and rapid breathing, typically occurring when levodopa medications reach their peak effect. This is typically accompanied by dyskinesia (writhing movements) of other body parts.

https://www.parkinson.org/understanding-parkinsons/non-movement-symptoms/breathing

Feeling 
Depressed

Depression is a part of Parkinson's itself, resulting from PD-related changes in brain chemistry. 50% of people with Parkinson's can suffer from depression. This can also be a symptom during the menstrual cycle, peri-menopause, menopause and post menopause for some women with Parkinson's.

https://www.parkinson.org/understanding-parkinsons/non-movement-symptoms/depression

Compulsive
Impulsive 
Behaviours

Certain medications are thought to be linked to compulsive and impulsive behaviour, in particular dopamine agonists and, in some cases, levodopa. Compulsive behaviours can include excessive shopping, gambling, eating and sex.

Feeling Dizzy
or Faint

Some people with Parkinson's can suffer from dizziness and vertigo. Orthostatic hypotension (OH) is the most commonly overlooked cause of dizziness in people with Parkinson’s. OH is a persistent drop in blood pressure that occurs upon moving from sitting to standing or from lying down to sitting up or standing. Certain medications can also cause these symptoms or can occur after Deep Brain Stimulation (DBS). Symptoms can be caused by low blood pressure for reasons other than OH such as anxiety, cold, flu, dehydration, heart conditions, migraine, and more.

https://www.parkinson.org/understanding-parkinsons/non-movement-symptoms/vertigo

Lack of 
interest
(Apathy)

Apathy is a feeling of indifference or lack of interest or motivation in activities. It can be a Parkinson's symptom for some people.

https://www.parkinson.org/understanding-parkinsons/non-movement-symptoms/apathy

Lack of 
joy 
(Anhedonia)

Dopamine is a plays a large role in our ability to experience pleasure. Thus the lack of dopamine in some people with Parkinson's can limit the ability to enjoy things.

https://www.medicalnewstoday.com/articles/320737#What-does-anhedonia-feel-like?

Mood
swings

Parkinson's causes a decrease in dopamine and this can affect mood including feelings of irritability. This can also be a symptom during the menstrual cycle, peri-menopause, menopause and post menopause for some women with Parkinson's.

https://www.med.upenn.edu/pdmdc/assets/user-content/mood.pdf

Food, Digestion and Weight

Bloated

Stomach bloating can be common in Parkinson's disease due to slow emptying of the stomach and slow movement of the intestines. It can be worsened by constipation, a bacteria in the stomach called Helicobacter Pylori or overgrowth of less healthy bacteria in the intestines. This can also be a symptom during the menstrual cycle, peri-menopause, menopause and post menopause for some women with Parkinson's.

https://www.parkinsonseurope.org/about-parkinsons/symptoms/non-motor-symptoms/bowel-problems/

Constipated

Parkinson's can affect the digestive system. When digestive tract movement slows in Parkinson's, it may lead to constipation. This can also be a symptom during the menstrual cycle, peri-menopause, menopause and post menopause for some women with Parkinson's. 

https://www.parkinson.org/understanding-parkinsons/non-movement-symptoms/constipation

Diarrohea

Diarrohea can be a side effect of Parkinson's medication. This can also be a symptom during the menstrual cycle, peri-menopause, menopause and post menopause for some women with Parkinson's.

https://www.parkinsonseurope.org/about-parkinsons/symptoms/non-motor-symptoms/bowel-problems/

Excessive salivation (Sialorrhea)

Sialorrhea, is when your saliva builds up in your mouth due to not swallowing enough and can affect some people with Parkinson's.

https://www.parkinsons.org.uk/information-and-support/your-magazine/experts/managing-drooling-when-you-have-parkinsons

Feeling Dizzy
or Faint

Some people with Parkinson's can suffer from dizziness and vertigo. Orthostatic hypotension (OH) is the most commonly overlooked cause of dizziness in people with Parkinson’s. OH is a persistent drop in blood pressure that occurs upon moving from sitting to standing or from lying down to sitting up or standing. Certain medications can also cause these symptoms or can occur after Deep Brain Stimulation (DBS). Symptoms can be caused by low blood pressure for reasons other than OH such as anxiety, cold, flu, dehydration, heart conditions, migraine, and more.

https://www.parkinson.org/understanding-parkinsons/non-movement-symptoms/vertigo

Food 
Cravings

Craving for sugary foods is common in Parkinson's. They can be caused by several reasons such as the impact of Parkinson's medication, lower dopamine levels during off times and or low mood. This can also be a symptom during the menstrual cycle, peri-menopause, menopause and post menopause for some women with Parkinson's. 

https://davisphinneyfoundation.org/sugar-cravings-parkinsons/

Increased
Appetite

Increased appetite can occur due to impulse control disorders from certain Parkinson's medications and can lead to over eating or can occur after Deep Brain Stimulation (DBS), a treatment for Parkinson's.

https://www.parkinsons.org.uk/information-and-support/maintaining-healthy-weight

Loss of
Smell
(Hyposmia)

Many people with Parkinson's report a loss of smell. This can affect the ability to taste food and drink. This can also be a symptom during the menstrual cycle, peri-menopause, menopause and post menopause for some women with Parkinson's.

https://www.parkinson.org/understanding-parkinsons/non-movement-symptoms/loss-of-smell

Loss of taste (ageusia)

Some people with Parkinson's report an inability to taste food and drink. This can also be related to a lack of the ability to smell foods. This can also be a symptom during the menstrual cycle, peri-menopause, menopause and post menopause for some women with Parkinson's.

https://www.cedars-sinai.org/health-library/diseases-and-conditions/s/smell-and-taste-disorders.html

Nausea

Nausea is a sense of unease in the stomach and can occur with Parkinson's. This can be a Parkinson's medication side effect or due to a slower emptying of food out of the stomach or due to orthostatic hypotension. 

https://www.parkinson.org/understanding-parkinsons/non-movement-symptoms/constipation

Reduced 
appetite

Reduced appetite is a common problem for people with Parkinson's that can affect your ability to consume an adequate amount of food and fluid. There are many reasons your appetite may decrease with Parkinson's including low mood, nausea, decreased sense of smell, constipation, swallowing difficulties, fatigue and certain medications.

https://www.apdaparkinson.org/article/weight-loss-parkinsons-disease/#:~:text=Decreased%20appetite%20in%20PD%20can%20have%20many%20causes%3A&text=Apathy%20or%20the%20state%20of,leading%20to%20decreased%20food%20intake.

Swallow
issues

Swallowing problems can affect many people with Parkinson's. These can include coughing, choking or throat clearing when eating or drinking. Some people may feel like the food is getting "stuck" as it goes down.

https://www.parkinsons.org.uk/information-and-support/eating-swallowing-and-saliva-control

Weight 
Gain

Weight gain can occur due to increase in craving sugary foods or due to side effects of drugs such as agonists or after Deep Brain Stimulation (DBS).

https://www.parkinsons.org.uk/information-and-support/maintaining-healthy-weight

Weight
Loss

Weight loss can occur due to loss in appetite, or excessive motor symptoms such as tremor or rigidity or from side effects of drugs such as dyskinesias (jerky movements).

https://www.apdaparkinson.org/article/weight-loss-parkinsons-disease/#:~:text=Decreased%20appetite%20in%20PD%20can%20have%20many%20causes%3A&text=Apathy%20or%20the%20state%20of,leading%20to%20decreased%20food%20intake.

Mental alertness and control

Difficulty
concentrating

Some people with Parkinson's may have more difficulty finding the right words when talking or writing when the dopamine levels drop in between doses of levodopa medication. This can also be a symptom during the menstrual cycle, peri-menopause, menopause and post menopause for some women with Parkinson's. 

https://www.parkinson.org/understanding-parkinsons/non-movement-symptoms/cognitive

Difficulty
finding
words

Some people with Parkinson's may have more difficulty finding the right words when talking or writing when the dopamine levels drop in between doses of levodopa medication. This can also be a symptom during the menstrual cycle, peri-menopause, menopause and post menopause for some women with Parkinson's.

https://www.parkinson.org/understanding-parkinsons/non-movement-symptoms/cognitive

Difficulty
multi-tasking

Some people with Parkinson's may have more difficulty multi-tasking when the dopamine levels drop in between doses of levodopa medication. This can also be a symptom during the menstrual cycle, peri-menopause, menopause and post menopause for some women with Parkinson's.

https://www.parkinson.org/understanding-parkinsons/non-movement-symptoms/cognitive

Impulse control disorder (e.g. binge eating, shopping)

Impulse Control Disorders (ICDs) are closely related to use of Parkinson's medications (in particular agonists), and most commonly include: gambling, excessive spending, over eating or hypersexuality.

https://www.parkinson.org/living-with-parkinsons/emotional-mental-health/impulse-control

Lower tolerance for noise or light

Light sensitivity can be caused by dry eye from Parkinson's. Low tolerance for noise or light can also be a symptoms during the menstrual cycle, peri-menopause and menopause for some women with Parkinson's.

https://www.aao.org/eye-health/ask-ophthalmologist-q/can-light-sensitivity-from-parkinson-s-be-treated#:~:text=Light%20sensitivity%20can%20be%20caused,for%20other%20diseases%20will%20help.

Brain fog (Slowed thinking)

Brain fog is a condition that can abruptly affect the ability of people with Parkinson’s to focus and think clearly. This can also be a symptom during the menstrual cycle, peri-menopause and menopause for some women with Parkinson's. A strong contributing factor to brain fog is fatigue. 

https://www.parkinson.org/understanding-parkinsons/non-movement-symptoms/cognitive

Pain

Backache

Parkinson's can contribute to factors that can cause or worsen lower back pain, such as rigidity (stiffness) of the trunk muscles or dystonia (abnormal muscle contractions caused by Parkinson's or Parkinson's medications) of the trunk muscles. This can also be a symptom during the menstrual cycle, peri-menopause, menopause and post menopause for some women with Parkinson's.

https://www.parkinson.org/understanding-parkinsons/non-movement-symptoms/pain

Headache

Headaches can happen for some people with Parkinson's and are sometimes caused by Parkinson's medications. They may also be related to musculoskeletal (muscle) pain in the neck and shoulders. This can also be a symptom during the menstrual cycle, peri-menopause, menopause and post menopause for some women with Parkinson's

 

https://www.parkinson.org/understanding-parkinsons/non-movement-symptoms/pain.

Muscle &
joint pains

Pain in Parkinson's can be musculoskeletal, in which the pain results from problems with the muscles, bones or joints or cramping pain, which is due to abnormal muscle contractions caused by Parkinson's or the medications used to treat it. 

https://www.parkinson.org/understanding-parkinsons/non-movement-symptoms/pain

Pain in
your body

Pain in Parkinson's can be musculoskeletal, in which the pain results from problems with the muscles, bones or joints or cramping pain, which is due to abnormal muscle contractions caused by Parkinson's or the medications used to treat it; It can also be nerve pain & central pain. Pain can get worse when the dopamine levels drop in between doses of levodopa medication.

https://www.parkinson.org/understanding-parkinsons/non-movement-symptoms/pain

Pins & Needles
 

Some people with Parkinson's report pins and needles or perhaps numbness in a limb. This can also be a symptom during peri-menopause, menopause and post menopause for some women with Parkinson's.

https://www.apdaparkinson.org/article/peripheral-neuropathy-parkinsons-disease/

Skin

Dry skin (Seborrheic dermatitis)

If skin becomes extremely oily it may also be red, flaky and itchy - this is known as seborrheic dermatitis and can be a symptom of Parkinson's. Skin may also become flaky, crusty or may peel. This mainly affects the scalp, face (particularly around the nose, the eyebrows and eyelids), ears (inside and out), chest and folds in the skin such as under the arms, breasts and groin. This can also be a symptom during peri-menopause, menopause and post menopause for some women with Parkinson's.

https://www.parkinson.org/understanding-parkinsons/non-movement-symptoms/skin

Excessive
Sweating

Parkinson's can affect the part of the nervous system that controls sweating which can lead to excessive sweating or hot flushes (known as hyperhidrosis). It most often happens gets worse when the dopamine levels drop in between doses of levodopa medication. Some people can also experience sweating at night. This can also be a symptom during peri-menopause, menopause and post menopause for some women with Parkinson's.

https://www.parkinson.org/understanding-parkinsons/non-movement-symptoms/skin

Hot flushes

Parkinson's can affect the part of the nervous system that controls sweating which can lead to excessive sweating or hot flushes (known as hyperhidrosis). It most often happens gets worse when the dopamine levels drop in between doses of levodopa medication. Some people can also experience sweating at night. This can also be a symptom during peri-menopause, menopause and post menopause for some women with Parkinson's.

https://www.parkinson.org/understanding-parkinsons/non-movement-symptoms/skin

Lack of sweating (hypo hidrosis)

Some people with Parkinson's may not sweat enough. This may be a side-effect of anticholinergics, a type of medication used to treat Parkinson's.

https://www.parkinson.org/understanding-parkinsons/non-movement-symptoms/skin

Blurry
vision

 

Blurry vision can be caused by dry eyes due to decreased blinking is associated with Parkinson's. It can also be caused by Parkinson medication especially anticholinergics. This can also be a symptom during the menstrual cycle, peri-menopause, menopause and post menopause for some women with Parkinson's.

https://www.parkinson.org/understanding-parkinsons/non-movement-symptoms/vision

Dry Eyes
 

Dry eyes due to decreased blinking is associated with Parkinson's .This can also be a symptom during the menstrual cycle, peri-menopause, menopause and post menopause for some women with Parkinson's.

https://www.parkinson.org/understanding-parkinsons/non-movement-symptoms/vision

Sleep

Excessive daytime sleepiness

Daytime sleepiness related to Parkinson's may arise for many reasons, including getting a poor night's sleep or the use of Parkinson's medications, especially dopamine agonists. Excessive daytime sleepiness can occur because of night time sleep issues or due to your medication.

https://www.parkinson.org/understanding-parkinsons/non-movement-symptoms/sleep-disorders

Fatigue

About 50% of people with Parkinson's report that fatigues as a major problem. It can include physical fatigue: feeling deeply tired or weary and mental fatigue or mental tiredness makes it difficult to concentrate. Fatigue can may worsen with fluctuations. Mental fatigue: mental tiredness that makes it difficult to concentrate.

https://www.parkinson.org/understanding-parkinsons/non-movement-symptoms/fatigue

Sleep disordered breathing (sleep apnoea)

Sleep apnoea is identified as pauses of breathing during sleep which last at least 10 seconds each and which occur five times or more. Common symptoms include loud snoring, pause in breathing during night sleep and restless sleep. This can affect up to 40% of people with Parkinson's.

https://www.parkinson.org/understanding-parkinsons/non-movement-symptoms/sleep-disorders

Difficulty in sleeping (Insomnia)

Insomnia is the inability to sleep. It includes difficulty falling asleep and staying asleep, as well as waking up too early. Problems with sleep maintenance — such as frequently waking throughout the night with difficulty falling back to sleep — are the most common type of insomnia in people with Parkinson's.

https://www.parkinson.org/understanding-parkinsons/non-movement-symptoms/sleep-disorders

Night
sweats

 

Night sweats are common is some people with Parkinson's. This can also be a symptom during the menstrual cycle, peri-menopause, menopause and post menopause for some women with Parkinson's. 

https://www.parkinson.org/understanding-parkinsons/non-movement-symptoms/skin

Talking, yelling, physically acting out while asleep

Rapid eye movement, or REM, sleep is the part of the sleep cycle when dreaming occurs. Usually, the only part of the body that moves during REM sleep is the eyes. People with rapid eye movement sleep behavior disorder (RBD) do not have the normal relaxation of the muscles during their dreams. Therefore, they act out their dreams during REM sleep. People with RBD may shout, hit or kick their bed partner or grind their teeth. Sometimes, in moderate to severe RBD, people may have aggressive, violent behaviors, like getting out of bed and attacking their bed partner. About half of people with PD suffer from RBD.

https://www.parkinson.org/understanding-parkinsons/non-movement-symptoms/sleep-disorders

Urinary and genital 

Less interest in sex (Low Libido)

Low libido is a common symptom in Parkinson's. This can also be a symptom during the menstrual cycle, peri-menopause, menopause and post menopause for some women with Parkinson's. 

https://www.parkinsonseurope.org/living-well/wellbeing/relationships-and-communication/intimacy-sex-and-sensuality/

Sudden
urge to urinate

You may feel the need to urinate immediately, at times without warning. This means that you cannot 'hold on' as you might do normally when you feel the urge to go. This can happen at night time too and is called nocturia. This can be a common symptom of Parkinson's. This can also be a symptom during peri-menopause, menopause and post menopause for some women with Parkinson's. 

https://www.parkinsonseurope.org/about-parkinsons/symptoms/non-motor-symptoms/bladder-problems/

Vaginal dryness

 Parkinson's can lead to vaginal dryness in some females. This can also be a symptom during peri-menopause, menopause and post menopause for some women with Parkinson's. 

Hormones & their impact on women with Parkinson's

Women with Parkinson's experience hormonal symptoms during the menstrual cycle and the peri-menopause, menopause and post menopause that can mimic Parkinson's symptoms or seem to exacerbate or ease Parkinson's symptoms. Click here for more information.

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